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Blood Pressure Vitamins

Low Vitamin D Linked to High Blood Pressure

10 years, 9 months ago

9139  0
Posted on Jul 08, 2013, 6 a.m.

A large-scale international genetic study confirms a causal association between low levels of vitamin D and hypertension (high blood pressure).

Hypertension (high blood pressure) is a complex medical condition, which may result as a culmination of factors including body weight, salt and water retention, mineral levels, etc.  Vimal Karani Santhanakrishnan, from the Institute of Children Health at the University College London (United Kingdom), and colleagues have completed a large genetic analysis demonstrated that individuals with genes linked to lower vitamin D levels are more likely to have hypertension mediated by low vitamin D. Among the 158,846 individuals studied, every 10% increase in serum 25-hydroxyvitamin D concentrations associated with a 0.24 mmHg decrease in diastolic blood pressure, and an 8.1% decrease in the risk of developing hypertension.  The study authors submit that they present “a rich data set showing a relationship between a specific genetic polymorphism and blood pressure,” suggesting that their findings attest to a causal association between low levels of vitamin D and high blood pressure.

Santhanakrishnan VK, et al. "A causal association between vitamin D status and blood pressure: a Mendelian randomization study in up to 150,846 individuals" [Abstract #C18.2].  Presented at European Society of Human Genetics, 12 June 2013.

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