Improving significantly on an early prototype, Johns Hopkins University researchers have found a new way to join two unrelated proteins to create a molecular switch, a nanoscale "device" in which one biochemical partner controls the activity of the other. Lab experiments have demonstrated that the new switch performs 10 times more effectively than the early model and that its "on-off" effect is repeatable.
Improving significantly on an early prototype, Johns Hopkins University researchers have found a new way to join two unrelated proteins to create a molecular switch, a nanoscale “device” in which one biochemical partner controls the activity of the other. Lab experiments have demonstrated that the new switch performs 10 times more effectively than the early model and that its “on-off” effect is repeatable.
http://www.sciencedaily.com/releases/2004/12/041203085049.htm
