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Growth Hormone Therapy Improves Lipids Profile

Among adults diagnosed with growth hormone deficiency, a three-year long HGH replacement regimen markedly reduced total cholesterol, LDL, and triglycerides.

Adult growth hormone deficiency is a defined syndrome marked by an adverse lipids profile, changes in body fat distribution, and premature atherosclerosis,  At the 92 Annual Meeting of the Endocrine Society (ENDO 2010), British researchers report that adults with growth hormone deficiency treated with human growth hormone (hGH) therapy experience a variety of metabolic benefits.  Victor Oguntolu, from Kings College University Hospital (United Kingdom), and colleagues studied 32 men and 38 women who had completed at least three years of treatment with hGH, measuring their hormone levels and tracking changes in lipids profile, for a three-year period.  Observing that: “Significant improvement was observed in all lipid parameters after six months,” the researchers reported that: “Further reduction in [total cholesterol], LDL [low density lipoproteins],  and Triglycerides occurred between 12, and 36 months.”

Oguntolu V, et al "The effect of a 3-year growth hormone replacement on lipid profile of adults with growth hormone deficiency" ENDO 2010; Poster 1-267.

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