Previous studies of bitter orange (Citrus aurantium), containing the alkaloid p-synephrine, have suggested potential utility for weight management. Sidney J. Stohs, from Creighton University (Nebraska, USA), and colleagues tested the potential of p-synephrine alone, or p-synephrine plus the citrus flavonoids naringin and hesperidin, on the metabolic rate of 50 study subjects. Results showed that the p-synephrine alone increased the metabolic rate by 7%, ascompared to placebo. When 50mg of p-synephrine was consumed with 600 mg naringin and 100 mg hesperidin, the metabolic rate was almost 18% higher than the control group. No adverse effects to heart rate or blood pressure were observed. The researchers propose that: “This unusual finding of a thermogenic combination of ingredients that elevated metabolic rates without corresponding elevations in blood pressure and heart-rates warrants longer term studies to assess its value as a weight control agent.”
Citrus Extracts Help Promote Healthy Metabolic Function
Bitter orange extracts plus the citrus flavonoids, naringin and hesperidin, may boost metabolic rates without affecting blood pressure.
Sidney J. Stohs, Harry G Preuss, Samuel C. Keith, Patti L. Keith, Howard Miller, Gilbert R. Kaats. “Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes.” Int. J. Med. Sci. 2011; 8: 295-301
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