April 29, 2021 View Online
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The first non-invasive biomarker to track and verify efficacy of senolytic drugs

 

The discovery is expected to play a major role in efforts to develop treatments that would battle a myriad of chronic age-related conditions

 
 
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Tiny implantable tool for light-sheet imaging of brain activity

Tools that allow neuroscientists to record and quantify functional activity within the living brain are in great demand. Traditionally, researchers have used techniques such as functional magnetic resonance imaging, but this method cannot record neural activity with high spatial resolution or in moving subjects. In recent years, a technology called optogenetics has shown considerable success in recording neural activity from animals in real time with single neuron resolution.

Optogenetic tools use light to control neurons and record signals in tissues that are genetically modified to express light-sensitive and fluorescent proteins. However, existing technologies for imaging light signals from the brain have drawbacks in their size, imaging speed, or contrast that limit their applications in experimental neuroscience.

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Simple Flip of Genetic Switch Determines Longevity in Animals

Scientists pinpoint the start of aging, discover it is not a slow series of random events.

  • Cellular and organismal slide begins during early adulthood at reproductive maturity
  • Study indicates ‘aging is not a continuum of various events’
  • Findings have implications for humans and quality of life
  • Blocking the switch enhances stress resilience, protects aging cells and delays disease
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Supplement targets gut microbes to boost growth in malnourished children

  • Malnourished children who received a food supplement designed to boost normal gut microbes gained more weight than those given a standard nutritional supplement.
  • The microbiome-targeted supplement also raised levels of proteins in the blood associated with bone, cartilage, and brain health.
  • Longer studies are needed to see if these improvements lead to better physical and cognitive health as children age.
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Anti-aging compound that improves metabolic health in mice improves muscle glucose metabolism in people

According to a news release, in the first clinical trial of nicotinamide mononucleotide (NMN), researchers at Washington University School of Medicine in St. Louis have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people. Further studies underway to determine the extent of clinical benefits.

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Redefining Medicine Episode 58 Special Guest Ronald Klatz MD, DO

A4M Redefining Medicine: Dr.Klatz Discusses The Beginning Of Anti-Aging Medicine and Chronic Diseases

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Human Growth Hormone

Immortality Now: Grow Younger with HGH

Learn how Energy Medicine can be used to improve your own health and well–being

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Medical Editors

The American Academy of Anti-Aging Medicine (A4M) publishes Longevity Magazine®. A unique feature of The World Health Network, www.worldhealth.net, the A4M's educational website. Longevity Magazine e-Journal is an electronic publication that provides timely and informative news relating to wellness, prevention, and biotech advancements in longevity. Established in 1991 and comprised of 26,000 member physicians, health practitioners, and scientists representing 120 nations worldwide, The American Academy of Anti-Aging Medicine, Inc. (A4M) is a non-profit medical organization dedicated to the advancement of technology to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. A4M is also dedicated to educating physicians, scientists, and members of the public on anti-aging issues. Although A4M seeks to disseminate information on many types of medical treatments, it does not promote or endorse any specific treatment nor does it sell or endorse any commercial product .

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