Anti-Aging Research Science
TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling
9 years, 9 months ago
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Posted on Jul 20, 2014, 2 p.m.
Neuroendocrine circuit controls longevity and the age-dependent onset of metabolic decline via the pain-transducing channel TRPV1 [mouse]
TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling. Pharmacologic inactivation of CGRP receptors can restore metabolic health.
Riera CE, Huising MO, Follett P, Leblanc M, Halloran J, Dillin A, et al. Cell. 2014 May 22;157(5):1023-36.
