Rick Simpson Oil, commonly known as RSO, has become one of the most discussed cannabis products in recent years. Named after a Canadian engineer who popularized a homemade cannabis extraction method in the early 2000s, RSO is a thick, dark oil made from the whole cannabis plant. Unlike many refined cannabis products on the market today, RSO retains a broad range of cannabinoids, terpenes, and plant compounds. That profile is why advocates often describe it as a full spectrum extract.
But what does the research actually say? And how are everyday consumers choosing to use it?
What Makes RSO Different from Other Cannabis Products
RSO stands apart from typical cannabis oils and tinctures because of its extraction method and concentration. Most commercial cannabis oils isolate specific cannabinoids like THC or CBD. RSO, by contrast, is designed to preserve as much of the original plant profile as possible. The result is a highly concentrated product that contains a wide spectrum of compounds found naturally in the cannabis plant.
This distinction matters because of what researchers call the “entourage effect,” a theory suggesting that cannabinoids and terpenes may interact differently when consumed together rather than in isolation. While peer reviewed research on this concept is still developing, it has driven significant consumer interest in whole plant extracts like RSO.
What the Research Landscape Looks Like
Interest in RSO has grown alongside a broader wave of cannabis research, though it is important to note that large scale clinical trials specifically focused on RSO remain limited. Most of the published scientific literature examines individual cannabinoids rather than full spectrum preparations.
That said, preliminary studies and preclinical research have explored how certain cannabinoids interact with the body’s endocannabinoid system. Organizations like the National Institutes of Health have funded studies examining cannabinoid compounds in laboratory and animal models, though translating those findings to human outcomes requires significantly more investigation.
For consumers considering RSO, understanding RSO dosing is an essential starting point. Because RSO is highly concentrated, most guides recommend beginning with very small amounts and adjusting gradually over time. The Oregon Health Authority provides consumer resources on cannabis safety and responsible use, which can be a helpful reference for anyone exploring concentrated products for the first time.
How People Are Actually Using RSO
One of the reasons RSO has gained traction is its versatility. Unlike products designed for a single method of consumption, RSO can be used in several ways depending on individual preference.
The most common approaches include sublingual application, where a small amount of oil is placed under the tongue for absorption. Some consumers prefer adding RSO to food or beverages, mixing it into a smoothie or a simple snack to mask the strong natural flavor. Others apply it topically to the skin, and capsule form is another option for those who want a measured, consistent dose without tasting the oil directly. Each method comes with its own considerations around timing, onset, and concentration.
For a more detailed breakdown of how to use RSO, education focused dispensaries like Urban Farmacy in Portland, Oregon offer practical guidance tailored to different experience levels.
What to Keep in Mind Before Trying RSO
As with any concentrated cannabis product, there are a few practical considerations worth noting before getting started.
RSO is not regulated uniformly across all states. In Oregon, for example, all cannabis products sold through licensed dispensaries must meet testing and labeling requirements set by the Oregon Liquor and Cannabis Commission. Purchasing from a licensed retailer ensures the product has been tested for potency and contaminants, which matters especially with a concentrated extract.
Dosing matters more with RSO than with many other cannabis products. Because of its concentration, even a small difference in the amount consumed can significantly change the experience. Starting with a very small amount and increasing slowly is the most widely recommended approach among cannabis educators and dispensary professionals.
Finally, RSO is not a substitute for medical advice. While consumer interest in RSO continues to grow, anyone with specific health concerns should consult a qualified healthcare provider before incorporating any cannabis product into their routine.
The Bottom Line
RSO occupies a unique space in the cannabis world. Its whole-plant extraction method, high concentration, and versatility have made it a product of genuine interest for both new and experienced cannabis consumers. While the scientific research specific to RSO is still catching up to consumer enthusiasm, the growing body of cannabinoid research suggests this is a space worth watching.
If you are exploring concentrated cannabis products for the first time, take the time to learn about proper dosing, understand your local regulations, and seek out knowledgeable, education focused resources. Making informed decisions starts with asking the right questions and knowing where to find trustworthy answers.
This article was written for WHN by Margo Amala is the owner and founder of Urban Farmacy, the locally owned cannabis dispensary she opened in NE Portland Oregon. It is one of Portland’s first medical dispensaries. She built the menu around Oregon grown, small batch, lab tested products and a welcoming space where nobody feels rushed or judged. She is an advocate for alternative medicine and the responsible informed use of cannabis.
As with anything you read on the internet, this article should not be construed as medical advice; please talk to your doctor or primary care provider before changing your wellness routine. WHN neither agrees nor disagrees with any of the materials posted. This article is not intended to provide a medical diagnosis, recommendation, treatment, or endorsement.
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