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Resveratrol Stabilizes Blood Sugar Levels

Supplementation with resveratrol, a bioactive polyphenol found in grapes and red wine, improves glycemic control as well as glycated hemoglobin (HbA1c) levels, among diabetic people.

Resveratrol is a potent polyphenol found in grapes and red wine, studies of which have previously associated cardiovascular anti-inflammatory benefits. Moola Joghee Nanjan, from the JSS College of Pharmacy (India), and colleagues enrolled 62 diabetic men and women, in a study in which each was randomly assigned to receive their standard oral hypoglycemic medications, with or without a supplement of resveratrol (250 mg per day), for a three-month. Among those supplemented with resveratrol, the average hemoglobin A1C (HbA1c, glycated hemoglobin) level was 9.65, compared to 9.99 in the control group. As well, those receiving resveratrol displayed a systolic blood pressure of 127.92 mmHg, compared to 139.71 mmHg among the controls. Further, resveratrol supplementation improved total cholesterol levels and total protein levels.  The study authors conclude that: “Oral supplementation of resveratrol is thus found to be effective in improving glycemic control and may possibly provide a potential adjuvant for the treatment and management of diabetes.”

Jayesh Kumar Bhatt, Sabin Thomas, Moola Joghee Nanjan. “Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus.”  Nutrition Research, Volume 32, Issue 7, July 2012, Pages 537-541.

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