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HomeAnti-AgingAnti-Aging Research ScienceResveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

Oral treatment with either resveratrol or aspirin represses the accumulation of tetraploid intestinal epithelial cells [mouse model of colon cancer]

The chemopreventive action of resveratrol and aspirin involves the elimination of tetraploid cancer cell precursors.

Lissa D, Senovilla L, Rello-Varona S, Vitale I, Michaud M, Pietrocola F, Boileve A, Obrist F, Bordenave C, Garcia P, Michels J, Jemaa M, Kepp O, Castedo M, Kroemer G.  Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3020-5.

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