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Cardio-Vascular Environment

Plastic BPA Linked to Narrowing of the Arteries

11 years, 6 months ago

11073  0
Posted on Sep 26, 2012, 6 a.m.

People with severe coronary artery disease have been found to have higher-than-normal levels of the plastic bisphenol-A (BPA) in their urine.

A British research team has established a link between the plastic bisphenol-A (BPA) and narrowing of the arteries. Professor David Melzer, Professor of Epidemiology and Public Health at the University of Exeter (UK), and colleagues compared urinary levels of BPA with grades of severity of coronary artery disease in 591 patients who participated in the Metabonomics and Genomics Coronary Artery Disease (MaGiCAD) study. Results showed that urinary BPA concentration was significantly higher in those with severe CAD compared to those with normal coronary arteries. Professor Melzer said: "Our latest study strengthens a growing body of work that suggests that BPA may be adding to known risk factors for heart disease. Full proof will be very difficult to get, as experiments on this in humans are not feasible." The study is one of many in recent years suggesting that BPA may pose a risk to health.

Melzer D, Gates P, Osborn NJ, et al. Urinary bisphenol A concentration and angiography-defined coronary aratery stenosis. PLoS ONE 7(8): e43378. doi:10.1371/journal.pone.0043378

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