Klotho is neuroprotective against Alzheimer's Disease [cell model]
Pre-treatment of neurons with the anti-aging protein Klotho can prevent neuron death in the presence of the toxic amyloid protein and glutamate.
The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System
Zeldich E, Chen CD, Colvin TA, Bove-Fenderson EA, Liang J, Tucker Zhou TB, Harris DA, Abraham CR. J Biol Chem. 2014 Jul 18. pii: jbc.M114.567321.
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