HomeAnti-AgingAnti-Aging Research ScienceThe metabolite -ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

The metabolite [alpha]-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

June 16, 2014

Anti-Aging Research Science

Alpha-ketoglutarate boosts longevity by about 50% [roundworm]

Alpha-ketoglutarate interferes with cellular energy production and mimicks the effects of severe calorie restriction.

Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Huang J, et al. Nature. 2014 May 14.

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