High-Salt Meals Impacts Cardiovascular Measures in 30 Minutes
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Posted on Oct 31, 2012, 6 a.m.
Australian team explores mechanism underlying why a salt laden meal raises flow mediated dilation in as little as half an hour.
Dietary salt is related to blood pressure , and cardiovascular disease and increased sodium intakes have been shown to impair vascular function. Previously, Kacie Dickinson, from the University of Adelaide (Australia), and colleagues demonstrated that a high-salt meal can significantly raise flow mediated dilation, a measure of endothelial function, in as little as 30 minutes. The team is exploring the mechanism behind this effect, with new evidence finding that plasma nitrate and nitrite remained steady after a high-salt meal, thus ruling out the nitric oxide pathway.
Dickinson KM, Clifton PM, Keogh JB. “Endothelial function is impaired after a high-salt meal in healthy subjects.” Am J Clin Nutr. 2011 Mar;93(3):500-5; and Dickinson et al, ESPEN Congress on Nutrition & Metabolism, October 2012.
