The combination of fatigue, increased irritability, and feeling demoralized is medically known as vital exhaustion. Randy Cohen, from Mt. Sinai St. Luke’s-Roosevelt (New York, USA), and colleagues investigated the relationship between vital exhaustion and first-time heart disease in 11 prospective studies that involved 60,610 people without heart disease. The studies had an average follow-up of 6.5 years. Data revealed that vital exhaustion associated with a 36% increase in risk for first-time cardiovascular disease, when compared to people not experiencing these three psychological factors. The study authors warn that: “[Vital exhaustion]/fatigue is a significant risk factor for incident [cardiovascular disease] in healthy subjects, comparable in potency to some of the other common psychosocial risk factors for cardiac disease.”
Feeling Frazzled May Raise Heart Disease Risk
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Fatigue, increased irritability, and feeling demoralized, may markedly raise a healthy man or woman's risk of first-time cardiovascular disease.
Jincy Thankachen, Chirag Bavishi, Randy Cohen, Alan Rozanski. “Vital Exhaustion and Incident Cardiovascular Disease: a Meta-Analysis” [Abstract #17412]. Presentation at American Heart Association's Scientific Sessions 2014, 17 Nov. 2014.