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Cancer Environment

Exposure to Cigarette Smoke Increases Risk of Colorectal Cancer

14 years, 4 months ago

10119  0
Posted on Dec 14, 2009, 6 a.m.

Study involving more than 184,000 people reveals that current smokers have a 27% increased risk of colorectal cancer and former smokers a 23% increased risk.

In that numerous studies have reported a 20% to 60% increase in risk of colorectal cancer associated with active smoking, Michael J. Thun, from the American Cancer Society (Georgia, USA), and colleagues followed 184,187 people for a thirteen-year period, to examine the relationship of cigarette smoking to incident colorectal cancer.  The researchers found that current smokers have a 27% increased risk of colorectal cancer and former smokers a 23% increased risk.  Additionally, the team found that those subjects who smoked for at least half a century were at the highest risk -- 38% higher than never smokers.  No increased risk was found among those who quit smoking before the age of 40, or who had not smoked for 31 or more years.

Lindsay M. Hannan, Eric J. Jacobs, Michael J. Thun.  “The Association between Cigarette Smoking and Risk of Colorectal Cancer in a Large Prospective Cohort from the United States.”  Cancer Epidemiol Biomarkers Prev December 2009 18:3362-3367; doi:10.1158/1055-9965.EPI-09-0661.

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