Tuesday, October 15, 2024

Exercise May Deter Dementia

Moderate exercise in middle-age may reduce a personu2019s odds of Alzheimeru2019s Disease.

A person with mild cognitive impairment (MCI) has a slight but noticeable and measurable decline in cognitive abilities, including memory and thinking skills. These changes are serious enough to be noticed by the individuals experiencing them or to other people, but they are not severe enough to interfere with daily life or independent function. People with MCI are at an increased risk of developing Alzheimer’s disease. Of the growing body of research concerning lifestyle and brain health, and also the possibility of reduced risk of Alzheimer’s and other dementias, perhaps the strongest and most consistent evidence exists for regular physical activity. Yonas E. Geda, from Mayo Clinic (Minnesota, USA), and colleagues investigated the relationship between timing of exercise (mid-life/50-65 vs. late-life/70 and above) and risk of new cases of dementia, among 280 older adults (median age 81 years) with MCI.  Study participants completed a questionnaire on the frequency and intensity of exercise during their lifetime. After following the participants for about three years, the researchers found that a history of moderate physical exercise in middle age was associated with a significantly decreased risk of MCI progressing to dementia.

Geda Y.  “Subjective Cognitive Impairment, APOE e4 Status, and Cognitive Aging: The Arizona APOE Cohort.”  Presentation at Alzheimer’s Association International Conference 2014, 14 July 2014.

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