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Women's Health Brain and Mental Performance Cardio-Vascular

Daily Aspirin Helps to Slow Cognitive Decline

6 years, 3 months ago

2046  0
Posted on Oct 31, 2012, 6 a.m.

Low-dose aspirin may help forestall cognitive decline, among elderly women at high cardiovascular risk.

Previously, studies report that low-dose aspirin demonstrates benefits in the prevention of cardiovascular disease. Anne Borjesson-Hanson, from the University of Gothenburg (Sweden), and colleagues studied 681 women, mean age 75 years, who were at high risk of a cardiovascular event.  At the study’s start, 18.9% of the women were on a low-dose aspirin regimen, for which these subjects demonstrated an average decline on the Mini Mental State Examination (a standard assessment tool for cognitive function) was −0.05 for women on low-dose aspirin compared with a decline of −0.95 for non-users, over a five-year period.  Among those specifically at high cardiovascular risk, the decline also was less for aspirin users (−0.33), as compared to non-users (−0.95).  Observing that” Women on regular low-dose [aspirin] declined less on [Mini Mental State Examination] at follow-up than those not on [aspirin],” the stuidy authors conclude that: “Low-dose [aspirin] treatment may have a neuroprotective effect in elderly women at high cardiovascular risk.”

Silke Kern, Ingmar Skoog, Svante Ostling,  Jurgen Kern, Anne Borjesson-Hanson.  “Does low-dose acetylsalicylic acid prevent cognitive decline in women with high cardiovascular risk? A 5-year follow-up of a non-demented population-based cohort of Swedish elderly women.”  BMJ Open 2012;2:5 e001288.

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