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Industry News Stem Cell Research

Customized Stem Cells Enable Anti-Aging R&D

7 years, 11 months ago

9482  0
Posted on May 24, 2016, 6 a.m.

A high-throughput robotic platform enables researchers to create thousands of patient-specific stem cells with less variability.

Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute have designed a revolutionary, high-throughput, robotic platform that automates and standardizes the process of transforming patient samples into stem cells.  The NYSCF Global Stem Cell ArrayTM is a highly efficient technology that automate the entire process of generating patient-specific stem cells while reducing variability resulting from manual manipulations. The system takes patient samples and turns them into cells that have the ability to become any other cell type in the body, induced pluripotent stem (iPS) cells. The Array can then turn these iPS cells into adult cell types in the body such as heart cells, neurons, and liver cells.  Submitting that: “We demonstrate that automated reprogramming and the pooled selection of polyclonal pluripotent cells results in high-quality, stable iPSCs,” the study authors write that: “The robotic platform we describe will enable the application of iPSCs to population-scale biomedical problems including the study of complex genetic diseases and the development of personalized medicines.”

Daniel Paull, Ana Sevilla, Hongyan Zhou, Aana Kim Hahn, Hesed Kim, Christopher Napolitano, et al.  “Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells.”  Nature Methods, 3 August 2015.

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