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Broccoli Extract May Shield Skin from UV Rays

Cancer-promoting effects of ultraviolet (UV) radiation is counteracted by ingestion of broccoli sprout extract, in a lab animal model.

Unprotected prolonged exposure to sunlight raises the risk of ultraviolet (UV) radiation to cause or accelerate skin aging as well as skin cancer. Albena T. Dinkova-Kostova, from Johns Hopkins University (Maryland, USA), and colleagues fed broccoli sprout extracts, high in glucoraphanin, a precursor to compounds in broccoli that have been identified as potent anti-carcinogens, to laboratory mice previously exposed to UV radiation.  The researchers found that a daily dose of 10 moles of glucoraphanin inhibited the subsequent development of skin tumors, with skin tumor incidence reduced by 25% and tumor volume by 70%.

Albena T. Dinkova-Kostova, Jed W. Fahey, Andrea L. Benedict, Stephanie N. Jenkins, Lingxiang Ye, Scott L. Wehage and Paul Talalay. “Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice.”   Photochem. Photobiol. Sci., 2010, 9, 597’ DOI: 10.1039/b9pp00130a.

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