Sphaeranthus indicus may reduce levels of inflammatory biomarkers.
Utilized for centuries in Ayurvedic medicine. Sphaeranthus indicus is a botanical agent with anti-inflammatory effects have been associated. Rai Ajit K. Srivastava, from Piramal Life Sciences (India), and colleagues found that Sphaeranthus indicus and its active ingredient (7-hydroxy frullanoide) decreased specific inflammatory biomarkers – namely, MCP-1, TNF-alpha, and Interleukin-6. The team also revealed that Sphaeranthus indicus inhibits the expression of intercellular adhesion molecule-1 (ICAM-1), low levels of which corresponds to less inflammation, by 54%. The study authors write that: “Our findings demonstrate that anti-inflammatory agents that lower pro-inflammatory proteins inhibit the progression of atherosclerosis.”
