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Anti-Cancer Effects of Enriched Yeast Identified

Selenium enrichment of yeast changes the expression of certain proteins, a number which have reported anti-cancer effects.

An essential trace element, selenium acts as an antioxidant to protect cells from the free radical damage that causes aging and is linked to many age-related diseases. Karam El-Bayoumy, from Penn State College of Medicine (Pennsylvania, USA), and colleagues performed proteomic analysis of both regular and selenium-enriched yeast. Finding that selenium-enriched yeast produced a change in 37 proteins, a number of which are involved in the carcinogenesis process, the team urges for preclinical animal models and pilot human clinical trials to ascertain the potential beneficial anti-cancer effects.

Karam El-Bayoumy, Arunangshu Das, Stephen Russell, Steven Wolfe, Rick Jordan, Kutralanathan Renganathan, et al.  “The effect of selenium enrichment on baker's yeast proteome.”  Journal of Proteomics, Volume 75, Issue 3, 4 January 2012, Pages 1018-1030.

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