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Anti-Aging Drug List (Archive As Per Dr.Klatz)

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Medications
Anti-Aging Drug List To be archived only, not published, as per Dr.Klatz. August.4.2018
Compound Name Synonyms Species Strain Dosage Avg Lifespan Change Max Lifespan Change Gender Significance Pubmed ID
Calcium gluconate Drosophila melanogaster Oregon R 0.001 M -3.7 Male 110607
Calcium gluconate Drosophila melanogaster Oregon R 0.01 M -13.2 Male 110607
Calcium lactate Drosophila melanogaster Oregon R 0.01 M -10.7 Male 110607
Calcium gluconate Drosophila melanogaster Oregon R 0.1 M -56.6 Male 110607
Calcium lactate Drosophila melanogaster Oregon R 0.001 M 1.8 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 1 M -9.3 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.1 M -5.2 Male 110607
Calcium lactate Drosophila melanogaster Oregon R 0.1 M -66.1 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.01 M 0 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.001 M 0 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.001 M -1.8 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.5M 2x/week 0 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.25M 2x/week 3.8 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.01M 2x/week 3.8 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.01 M 5.3 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.5 M 9.3 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.1 M 12.3 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.1 M 14.3 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.1 M 20.8 Male 110607
Lactic acid Drosophila melanogaster Oregon R 1M -32.7 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.25 M 22.2 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.5M -1.9 Male 110607
Gluconic acid Drosophila melanogaster Oregon R 0.01 M 7.2 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.001M 3.6 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.01M 3.6 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.001M 8 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.1M 14 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.01M 12 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.1M 15.5 Male 110607
Tartaric acid Drosophila melanogaster Oregon R 0.1M -72 Male 110607
Tartaric acid Drosophila melanogaster Oregon R 0.001M 0 Male 110607
Tartaric acid Drosophila melanogaster Oregon R 0.01M 6 Male 110607
Lactic acid Drosophila melanogaster Oregon R 0.25M 15.4 Male 110607
Diiodomethane Methylene iodide Drosophila melanogaster 10 µg/ml 29.3 412727
Polypeptide Pineal extract PPE Rattus norvegicus

0.5 mg, 5 times a week

 25 Female 575333
Citrate Sodium citrate; Citric acid Mytilina brevispina

0.25% on alternate days

 51.7 804507
Butylated hydroxytoluene Mus musculus BaLB/c 15.8 Female 448040
Edetate Calcium Disodium ethylene diamine tetra-acetic acid (di-sodium salt); EDTA Mytilina brevispina

0.25% on alternate days

 49.4 804507
Butylated hydroxytoluene Mus musculus BaLB/c 18.7 Male 448040
EGTA 1,2-di(2 aminoethoxy)ethane tetra-acetic acid Mytilina brevispina

0.25% on alternate days

 75.9 804507
Tartrate Sodium tartrate Mytilina brevispina

0.25% on alternate days

 43.7 804507
L-deprenyl Rattus norvegicus Fischer 344 0.0025 16.7 17 2118586
Cortisone Asplanchna brightwelli clone 4B61 400 µM -3.2 0 NS 2782995
Cortisone Asplanchna brightwelli clone 4B61 800 µM -6.3 0 NS 2782995
Cortisone Asplanchna brightwelli clone 4B61 50 µM 2.2 0 NS 2782995
Cortisone Asplanchna brightwelli clone 4B61 100 µM 20.8 0 2782995
Cortisone Asplanchna brightwelli clone 4B61 10 µM 0.7 0 NS 2782995
Cortisone Asplanchna brightwelli clone 4B61 200 µM 19.3 0 2782995
Ascorbic Acid Vitamin C Caenorhabditis elegans N2 80 µg/ml 0 3374177
Vitamin E D,1-alpha-tocopherol Caenorhabditis elegans N2 400 µg/ml 4 3374177
Vitamin E D,1-alpha-tocopherol Caenorhabditis elegans N2 100 µg/ml 9 3374177
Vitamin E D,1-alpha-tocopherol Caenorhabditis elegans N2 200 µg/ml 17 3374177
Vitamin E D,1-alpha-tocopherol Caenorhabditis elegans N2 200 µg/ml 17 3374177
Vitamin E D,1-alpha-tocopherol Caenorhabditis elegans N2 200 µg/ml 22 3374177
Vitamin E D,1-alpha-tocopherol Caenorhabditis elegans N2 200 µg/ml 23 3374177
Sodium hypophosphite Zaprionus paravittiger 1 mM -89.8 -94.9 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 500 mM -85.3 -78.6 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 500 mM -84.1 -78.1 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 100 mM -58.8 -54.8 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 60 mM -24.4 -11.2 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 1 mM -88.5 -91.4 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 10 mM -8.3 -1.7 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 10 mM -4.1 -1.4 Male NS 3721207
Sodium hypophosphite Zaprionus paravittiger 60 mM -24.2 -8.1 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 1 µM 1 6 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 100 mM -46.9 -47.2 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 10 µM 13 13.3 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 1 µM 5.3 5.7 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 10 µM 13.2 12.4 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 100 µM 18 21 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 5 mM 23.6 21.9 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 5 mM 25.4 19.7 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 1 mM 28.1 27 Female 3721207
Sodium hypophosphite Zaprionus paravittiger 1 mM 28.5 34.3 Male 3721207
Sodium hypophosphite Zaprionus paravittiger 100 µM 24.9 22.9 Male 3721207
Nordihydroguaiaretic acid NDGA Aedes aegypti 0.001% (w/v) 42.7 Female 3749035
Nordihydroguaiaretic acid NDGA Aedes aegypti 0.005% (w/v) 6.7 Female NS 3749035
Nordihydroguaiaretic acid NDGA Aedes aegypti 0.01% (w/v) 13.6 Female NS 3749035
Nordihydroguaiaretic acid NDGA Aedes aegypti 0.005% (w/v) 64.3 Male 3749035
Curare Asplanchna brightwelli 0.00% -24 3833547
Curare Asplanchna brightwelli 0.00% 26 3833547
Nordihydroguaiaretic acid NDGA Aedes aegypti 0.001% (w/v) 11.9 Male NS 3749035
Curare Asplanchna brightwelli 0.00% 32 3833547
Curare Asplanchna brightwelli 0.00% 34 3833547
Ethoxyquin Mus musculus C3H 0.5% w/w 18.1 Male 4927196
Vitamin E Asplanchna brightwelli 25µg / mL 21 6479253
Ethoxyquin Mus musculus C3H 0.5% w/w 19.9 Female 4927196
Thyroxin T4 Rattus norvegicus Wistar 0.5 µg/g bodyweight -3.5 Female 6632988
Thyroxin T4 Rattus norvegicus Wistar 0.5 µg/g bodyweight 6.9 Male 6632988
Thyroxin T4 Rattus norvegicus Wistar 1 µg/g bodyweight 8.4 Female 6632988
Thyroxin T4 Rattus norvegicus Wistar 2 µg/g bodyweight 11.1 Male 6632988
Thyroxin T4 Rattus norvegicus Wistar 2 µg/g bodyweight 11.6 Female 6632988
Thyroxin T4 Rattus norvegicus Wistar 1 µg/g bodyweight 16.1 Male 6632988
Butylated hydroxytoluene BHT Drosophila bipectinata 10 µM 4.3 Female 6656301
Butylated hydroxytoluene BHT Drosophila bipectinata 100 µM 13 Female 6656301
Butylated hydroxytoluene BHT Drosophila bipectinata 10 µM 4.8 Male 6656301
Butylated hydroxytoluene BHT Drosophila bipectinata 100 µM 14.3 Male 6656301
Butylated hydroxytoluene BHT Drosophila bipectinata 1000 µM 26.1 Female 6656301

Polypeptide Bovine Thymus extract

 Mus musculus C3H/Sn 0.5 mg 28 11.2 Female 6752596
Polypeptide Pineal extract PPE Mus musculus C3H/Sn 0.5 mg 31 14 Female 6752596
Thiazolidine carboxylic acid TCA Drosophila melanogaster Oregon R 0.3% wt/vol 31 6821144
Vitamin E Alpha-tocopherol Philodina

concentration of 10^ -4

 9.2 0 7428854
Kinetin Zaprionus paravittiger 3125 ppm -71 -47.1 Male 7488181
Butylated hydroxytoluene BHT Drosophila bipectinata 1000 µM 19 Male 6656301
Kinetin Zaprionus paravittiger 625 ppm -20 0 Male 7488181
Kinetin Zaprionus paravittiger 3125 ppm -65.7 -55.2 Female 7488181
Vitamin E Drosophila melanogaster Oregon R 0.4% wt/vol 14 6821144
Kinetin Zaprionus paravittiger 125 ppm -2.9 17.1 Male 7488181
Kinetin Zaprionus paravittiger 625 ppm -2.9 -13.2 Female 7488181
Kinetin Zaprionus paravittiger 125 ppm 22.9 15.8 Female 7488181
Kinetin Zaprionus paravittiger 25 ppm 14.2 12.9 Male 7488181
Sodium borate Drosophila melanogaster Oregon R 0.01 M -69.2 Male 7889879
Kinetin Zaprionus paravittiger 25 ppm 80 19.7 Female 7488181
Sodium borate Drosophila melanogaster Oregon R 0.05 M -51.9 Male 7889879
Sodium borate Drosophila melanogaster Oregon R 1 µM 0 Male NS 7889879
Sodium borate Drosophila melanogaster Oregon R 0.01 mM 1.5 Male 7889879
Sodium borate Drosophila melanogaster Oregon R 0.1 mM 3 Male 7889879
Sodium borate Drosophila melanogaster Oregon R 0.25 mM 9.5 Male 7889879
Sodium borate Drosophila melanogaster Oregon R 1 mM -21.2 Male 7889879
Sodium borate Mus musculus C57BL/6J 0.5mM 0.8 Male NS 7889879
L-deprenyl Selegiline Rattus norvegicus F344/DuCrj 0.5 mg/kg. 3 times a week 5.6 1 Male 8030852
Black tea extract Drosophila melanogaster Oregon R Instead of water 20.2 Male 8326745
Melatonin Mus musculus BALB/c NA 18.1 Female 8290600
Caffeine Drosophila melanogaster Oregon R 0.01 mg/ml -10.1 Male NS 8326745
Caffeine Drosophila melanogaster Oregon R 1 mg/ml -3.3 Male NS 8326745
Sodium borate Mus musculus C57BL/6J 0.1 mM -2.9 Male NS 7889879
Catechin Drosophila melanogaster Oregon R 0.1 mg/ml -8.5 Male NS 8326745
Caffeine Drosophila melanogaster Oregon R 0.1 mg/ml 1.7 Male NS 8326745
Catechin Drosophila melanogaster Oregon R 1 mg/ml -5.1 Male NS 8326745
Epicatechin Drosophila melanogaster Oregon R 0.01 mg/ml 1.8 Male NS 8326745
Catechin Drosophila melanogaster Oregon R 0.01 mg/ml -5.1 Male NS 8326745
Epicatechin Drosophila melanogaster Oregon R 0.1 mg/ml 3.7 Male NS 8326745
Epicatechin Drosophila melanogaster Oregon R 1 mg/ml 7.4 Male NS 8326745
Tannic acid Drosophila melanogaster Oregon R 1 mg/ml 0 Male NS 8326745
Green tea extract Drosophila melanogaster Oregon R Instead of water 8.6 Male 8326745
Tannic acid Drosophila melanogaster Oregon R 0.1 mg/ml 0 Male NS 8326745
Tannic acid Drosophila melanogaster Oregon R 1 mg/ml -2.9 Male NS 8326745

Tea (Camellia sinensis) extract

 Drosophila melanogaster Oregon R Instead of water 15.7 Male 8326745

Tea (Camellia sinensis) extract

 Drosophila melanogaster Oregon R 1:10 dilution 7 Male 8326745

Tea (Camellia sinensis) extract

 Drosophila melanogaster Oregon R Instead of water 20.2 Male 8326745
L-deprenyl Selegiline Rattus norvegicus F344/DuCrj 0.5 mg/kg. 3 times a week 15.1 Male 8423709
L-deprenyl Selegiline Mus musculus B6CBAF1 0.25 mg/kg 3x/week 7 7.5 Male NS 8914495
L-deprenyl Selegiline Mus musculus B6CBAF1 0.25 mg/kg 3x/week 3.9 31.2 Female NS 8914495
L-deprenyl Selegiline Mus musculus B6D2F1 0.25 mg/kg 3x/week 2.7 15.3 Male NS 8914495
Propyl gallate Zaprionus paravittiger 25 µg/ml 8.7 15.3 Female 8950031
Propyl gallate Zaprionus paravittiger 25 µg/ml 15.1 12.2 Male 8950031

Tea (Camellia sinensis) extract

 Drosophila melanogaster Oregon R Instead of water 12.2 Male 8326745
L-deprenyl Selegiline Mus musculus B6D2F1 0.25 mg/kg 3x/week -0.1 -0.7 Female NS 8914495
Butylated hydroxyanisole BHA Zaprionus paravittiger 100 mM -63.8 -53.7 Male 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 50 mM -45.9 -40.7 Female 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 50 mM -31.7 -46.3 Male 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 1 mM 1.7 0.8 Female NS 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 1 mM 4 1.3 Male NS 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 100 mM -57.2 -55.2 Female 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 5 mM 7.9 6.9 Female 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 5 mM 18.4 6.6 Male 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 25 mM 13.1 4.4 Female 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 10 mM 27 17.6 Male 9207858
Butylated hydroxyanisole BHA Zaprionus paravittiger 10 mM 15.1 27 Female 9207858
L-deprenyl Selegiline Mesocricetus auratus 0.05 mg/kg/day 16.4 Female 9258898
Butylated hydroxyanisole BHA Zaprionus paravittiger 25 mM 20.5 2.2 Male 9207858
L-deprenyl Selegiline Canis lupus familiaris Beagles 1 mg/kg 9307048
Ascorbic acid Vitamin C Paramecium tetraurelia 50 mg/L 12.1 6.7 9406982
Melatonin Paramecium tetraurelia 10 mg/L 20.8 14.8 9406982
Melatonin Paramecium tetraurelia 10 mg/L 10.8 5.1 9406982
Melatonin Paramecium tetraurelia 10 mg/L 22.8 20.9 9406982
N-acetyl-L-cysteine Drosophila melanogaster Oregon R 1 mg/ml 14.1 15.1 Male 9447249
Vitamin E Tocopherol Paramecium tetraurelia 25 mg/L 11.7 17.1 9406982
N-acetyl-L-cysteine Drosophila melanogaster Oregon R 100 µg/ml 16.8 15.1 Male 9447249
N-acetyl-L-cysteine Drosophila melanogaster Oregon R 10 mg/ml 26.8 24.5 Male 9447249
Ginkgo biloba extract EGb 761 Rattus norvegicus Fischer 344 50 mg/kg 17.4 Male 9469738
N-tert-butyl-alpha-phenylnitrone PBN; alpha phenyl-N-tert butyl nitrone Mus musculus C57BL/6J 0.25 mg/ml of water 3.8 5 Male 9614711
Epithalamin Pineal peptide Preparation Mus musculus C3H/Sn NA 31 9701766
Epithalamin Pineal peptide Preparation Drosophila melanogaster NA 16 9701766
Melatonin Paramecium tetraurelia 10 mg/L 17.9 NS 9406982
Rhodiola rosea extract Drosophila melanogaster

30 mg/mL every other day

 42.9 Male 9825229
Rhodiola rosea extract Drosophila melanogaster

30 mg/mL every other day

 28.6 Female 9825229
Melatonin Drosophila melanogaster Canton S 0.08% per unit mass culture medium 5.5 Female 10100152
Melatonin Drosophila melanogaster Canton S 0.08% per unit mass culture medium 4.8 Male 10100152
Epithalamin Pineal peptide Preparation Rattus norvegicus NA 25 9701766
Tocotrienol vitamin E; alpha-tocophero; alpha-tocotrienol; gamma-tocotrienol; and sigma-tocotrienol Caenorhabditis elegans N2 8 ug/ml 8.7 10843344
Tocotrienol vitamin E; alpha-tocophero; alpha-tocotrienol; gamma-tocotrienol; and sigma-tocotrienol Caenorhabditis elegans N2 80 ug/ml 19.8 10843344
EUK-134 Caenorhabditis elegans N2 0.05 mM 29 10968795
EUK-134 Caenorhabditis elegans N2 0.5 mM 38 10968795
EUK-134 Caenorhabditis elegans N2 0.05 mM 38 10968795
EUK-134 Caenorhabditis elegans N2 5 mM 52 10968795
EUK-134 Caenorhabditis elegans N2 5 mM 42 10968795
EUK-134 Caenorhabditis elegans N2 10 mM 52 10968795
Vitamin E Alpha-tocopherol acetate Caenorhabditis elegans N2 80 ug/ml 2.9 10843344
EUK-134 Caenorhabditis elegans N2 0.5 mM 54 10968795
EUK-8 Caenorhabditis elegans N2 10 mM 29 10968795
EUK-8 Caenorhabditis elegans N2 5 mM 29 10968795
EUK-8 Caenorhabditis elegans N2 0.05 mM 33 10968795
EUK-8 Caenorhabditis elegans N2 0.5 mM 38 10968795
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 5*10^-6 % 3.2 Female NS 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-9 % 7.1 Female NS 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-6 % 3.2 Female NS 11087911
EUK-8 Caenorhabditis elegans N2 5 mM 33 10968795
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-7 % 10.8 Male 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 5*10^-6 % 11.3 Male 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-7 % 11.8 Female 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-6 % 12.8 Male 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-8 % 13.4 Female 11087911
Melatonin Mus musculus CBA 20mg/l 5.4 7.5 Female 11445596
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-8 % 12 Male 11087911
Epitalon Ala-Glu-Asp-Gly Drosophila melanogaster Canton S 1*10^-9 % 16.6 Male 11087911
L-Glu-L-Trp dipeptide Rattus norvegicus

5 µg/rat. 5 times a week

 0 10.4 Female 11707921
D-glucosamine Saccharomyces cerevisiae W303R 0.5 mg/ml 0 NS 11805047
4-phenylbutyrate PBA Drosophila melanogaster Canton S 5 mM 40 41 11792861
D-glycerol Saccharomyces cerevisiae PSY316 1 M 49.8 12391171
Melatonin Drosophila melanogaster Oregon R 100 µg/ml 14 33 11909680
D-xylitol Saccharomyces cerevisiae PSY316 1 M 36.8 12391171
Glucose Dextrose; D-glucose Saccharomyces cerevisiae PSY316 10% 19.8 12391171
Glucose Dextrose; D-glucose Saccharomyces cerevisiae PSY316 20% 63.1 12391171
Carnosine Drosophila melanogaster D-32 200 mg/l 24.3 Male 12447464
Sorbitol D-sorbitol; Glucitol Saccharomyces cerevisiae PSY316 1 M 29.9 12391171
Carnosine Drosophila melanogaster D-32 0.2 mg/l 19.5 Male 12447464
Carnosine Drosophila melanogaster D-32 2 mg/l 26.4 Male 12447464
EUK-8 Caenorhabditis elegans N2 5 mM -83.9 12521609
EUK-8 Caenorhabditis elegans N2 5 mM -83.7 12521609
EUK-8 Caenorhabditis elegans N2 5 mM -81 12521609
EUK-8 Caenorhabditis elegans N2 0.5 mM -33.1 Male 12521609
EUK-8 Caenorhabditis elegans N2 0.5 mM -26.5 12521609
EUK-8 Caenorhabditis elegans N2 0.5 mM -26.6 12521609
EUK-8 Caenorhabditis elegans N2 0.5 mM -21.1 12521609
EUK-8 Caenorhabditis elegans N2 0.05 mM -12.9 Male 12521609
EUK-8 Caenorhabditis elegans N2 0.5 mM -10.7 12521609
EUK-8 Caenorhabditis elegans N2 0.05 mM -6.1 12521609
Carnosine Drosophila melanogaster D-32 200 mg/l Female NS 12447464
EUK-8 Caenorhabditis elegans N2 0.05 mM -5.7 NS 12521609
EUK-8 Caenorhabditis elegans N2 0.05 mM -0.9 NS 12521609
Butein Saccharomyces cerevisiae PSY316AT MAT_ 10 µM 31 12939617
EUK-8 Caenorhabditis elegans N2 0.05 mM -0.9 NS 12521609
EUK-8 Caenorhabditis elegans N2 0.05 mM 3 NS 12521609
Fisetin Saccharomyces cerevisiae PSY316AT MAT_ 10 µM 55 12939617
Resveratrol Saccharomyces cerevisiae PSY316AT MAT_ 10 µM 60.7 12939617
Resveratrol Saccharomyces cerevisiae PSY316AT MAT_ 100 µM 40 12939617
Resveratrol Saccharomyces cerevisiae PSY316AT MAT_ 500 µM 39.5 12939617
Resveratrol Saccharomyces cerevisiae PSY316AT MAT_ 10 µM 70 12939617
Royal Jelly Mus musculus C3H/HeJ 500 ppm ad libitum in diet 23.6 Male 12954483
Buformin Rattus norvegicus LIO 5 mg/day 7 5.5 Female 14618027
Phenformin Mus musculus C3H/Sn 2 mg, 5 times a week 21 26 Female 14618027
Coenzyme Q10 Q10 Caenorhabditis elegans N2 50 µg/ml 6 14706236
Vitamin E Caenorhabditis elegans N2 400 µg/ml 11 14706236
Coenzyme Q10 Q10 Caenorhabditis elegans N2 150 µg/ml 18 14706236
Coenzyme Q10 Q10 Caenorhabditis elegans N2 150 µg/ml 9 14706236
Tetrahydrocurcumin Mus musculus Sprague-Dawley 0.002 11.7 Male 15247057
Green tea polyphenols Mus musculus Sprague-Dawley 80 mg/L 6.4 Male 15247057
Fisetin Drosophila melanogaster Canton S 100 µm 23 15254550
Resveratrol Caenorhabditis elegans N2 100 µm 10 15254550
Resveratrol Drosophila melanogaster Canton S 100 µm 20 Female 15254550
Resveratrol Drosophila melanogaster Canton S 100 µm 16 Male 15254550
Trichostatin A Drosophila melanogaster Canton S 10 µM 23.3 37 Male 15346199
3,3′-thiodipropionic acid TDPA Asplanchna brightwelli clone 4B61 2 mM 10 0 15374519
Alpha-lipoic acid Lipoic acid Drosophila melanogaster Canton S 0.00005 12 5 Female 15328413
Trichostatin A Drosophila melanogaster Canton S 10 µM 27.3 37.9 Female 15346199
Vitamin E D-alpha-tocopherol Asplanchna brightwelli clone 4B61 3 mM 24.5 15374519
Vitamin E D-alpha-tocopherol Asplanchna brightwelli clone 4B61 3 mM 16.4 6.7 15374519
Galactose D-galactose Musca domestica 20 mg/ml -27.1 -27.1 Male 15547319
Galactose D-galactose Drosophila melanogaster 6.50% -16.6 -12.9 Male 15547319
3,3′-thiodipropionic acid TDPA Asplanchna brightwelli clone 4B61 2 mM 16.4 15374519
Aurintricarboxylic acid ATA Drosophila melanogaster Oregon R 0.5 mM 15 0 Male 15621204
Galactose D-galactose Musca domestica 20 mg/ml -19.8 -21.9 Female 15547319
3,3-diethyl-2-pyrrolidinone DEABL Caenorhabditis elegans N2 2 mg/ml 31 49 15653505
Ethosuximide Caenorhabditis elegans N2 4 mg/ml 35 37 15653505
Galactose D-galactose Drosophila melanogaster 6.50% -15.9 -17.1 Female 15547319
3,3-diethyl-2-pyrrolidinone DEABL Caenorhabditis elegans N2 2 mg/ml 31 49 15653505
Ethosuximide Caenorhabditis elegans N2 4 mg/ml 14 -2 15653505
Ethosuximide Caenorhabditis elegans N2 4 mg/ml 17 22 15653505
Ethosuximide Caenorhabditis elegans N2 4 mg/ml 35 37 15653505
Trimethadione Caenorhabditis elegans N2 4 mg/ml 47 57 15653505
Ethosuximide Caenorhabditis elegans N2 2 mg/ml 13 24 15653505
Trimethadione Caenorhabditis elegans N2 4 mg/ml 24 29 15653505
Trimethadione Caenorhabditis elegans N2 4 mg/ml -7 -10 NS 15653505
Trimethadione Caenorhabditis elegans N2 4 mg/ml 39 33 15653505
Trimethadione Caenorhabditis elegans N2 4 mg/ml 41 23 15653505
Resveratrol Saccharomyces cerevisiae BY4741 100 mg/ml 0 NS 15684413
Resveratrol Saccharomyces cerevisiae PSY316 100 mg/ml 0 NS 15684413
Resveratrol Saccharomyces cerevisiae W303R 100 mg/ml 0 NS 15684413
Trichostatin A TSA Drosophila melanogaster Canton S 10 µmol/L 15.6 Female 15695762
Resveratrol Caenorhabditis elegans N2 0.5 mM 14 16256736
Echinacea purpurea root Mus musculus BALB/cByJ 2 mg/day 28 Male 16041619
Trimethadione Caenorhabditis elegans N2 4 mg/ml 47 57 15653505
Resveratrol Caenorhabditis elegans N2 1 mM 17.8 16256736
2,4-dinitrophenol DNP Drosophila melanogaster Oregon R 0.008 20.2 0 16266268

Dauer-inducing Pheromone

 Caenorhabditis elegans N2 5% in food 13.3 16377915

Dauer-inducing Pheromone

 Caenorhabditis elegans N2 10% in food 26.7 16377915
Resveratrol Caenorhabditis elegans N2 0.1 mM 9.3 16256736

Crude BB extract (Vaccinium angustifolium)

 Caenorhabditis elegans fem-1(hc17) 1.5 mg/mL 37 16441844
Ampicillin Caenorhabditis elegans fem-1(hc17) 100µg/ml 34 16441844
Resveratrol Nothobranchius furzeri Gonarezhou 600 µg/g food 56 59 16461283
L-deprenyl Selegiline Rattus norvegicus F344/DuCrj 0.25 mg/kg. 3 times a week 8.1 Male 16463106
Tamarixetin Caenorhabditis elegans NA 28 16872777
L-deprenyl Selegiline Rattus norvegicus F344/DuCrj 0.25 mg/kg. 3 times a week 6.7 Female 16463106
Tocotrienol Tocotrienol rich fraction from palm oil Caenorhabditis elegans N2 NA 20 16872777
3,5-dihydroxy-4Í-acetoxy-trans-stilbene 3,5-hydroxy-4Í-acetoxy-stilbene Saccharomyces cerevisiae PSY316AT_ 10 µM 68.2 17156081
3,5-dihydroxy-4Í-thiomethyl-trans-stilbene 3,5-hydroxy-4Í-thiomethyl-stilbene Saccharomyces cerevisiae PSY316AT_ 10 µM 22.7 17156081
Ginkgo biloba extract EGb 761 Caenorhabditis elegans N2 100 µg/ml 8 16872777
Resveratrol Saccharomyces cerevisiae PSY316AT_ 10 µM 41.6 17156081
3,5-dihydroxy-4Í-ethyl-trans-stilbene 3,5-hydroxy-4Í-ethyl-stilbene Saccharomyces cerevisiae PSY316AT_ 10 µM 51.5 17156081
Resveratrol Saccharomyces cerevisiae PSY316AT_ 10 µM 33.9 17156081
Gamma-tocopherol Caenorhabditis elegans fem-1(hc17) 20 ug/ml 17 17169403
Alpha-lipoic acid Lipoic acid Caenorhabditis elegans N2 24 µM 24.2 14.3 17156833
Gamma-tocopherol Caenorhabditis elegans fem-1(hc17) 200 ug/ml 21 17169403
Vitamin E Tocopherol Caenorhabditis elegans N2 200 µg/mL 20.6 0 17169403
Epigallocatechin-3-gallate EGCG Caenorhabditis elegans N2 25 µM 4.8 4.8 NS 17156833
Vitamin E Tocopherol Caenorhabditis elegans N2 20 µg/mL 16.6 0 17169403
Pregnenolone PREG Caenorhabditis elegans N2 60 µg/mL 20 17266678
Vitamin E Alpha-tocopherol Drosophila melanogaster Canton S 100 ug/ml 2 Female 17169403
4-dafachronic acid Caenorhabditis elegans N2 250 nM 0 2.6 17360327
4-dafachronic acid Caenorhabditis elegans N2 250 nM 16.6 28 17360327
Creatine Mus musculus C57BL/6J 0.01 8 3.5 Female 17416441
Green tea extract Longjing green tree catechin extract Drosophila melanogaster Oregon-R-C 5 mg/ml 7.8 5.3 17440995
Resveratrol Caenorhabditis elegans N2 50 µM 50.8 29.2 17460219
Green tea extract Longjing green tree catechin extract Drosophila melanogaster Oregon-R-C 10 mg/ml 15.7 5.3 17440995
Green tea extract Longjing green tree catechin extract Drosophila melanogaster Oregon-R-C 1 mg/ml 5.9 5.3 17440995
Nicotinamide riboside NR Saccharomyces cerevisiae BY4741 10 µM 20 NS 17482543
Tetrahydrocurcumin Mus musculus C57BL/6J 0.002 11.7 6.5 17516143
Resveratrol Caenorhabditis elegans N2 100 µM 7.4 17875315
Resveratrol Caenorhabditis elegans N2 100 µM 7.5 17875315
Resveratrol Caenorhabditis elegans N2 100 µM 8.1 NS 17875315
Resveratrol Caenorhabditis elegans N2 100 µM 3.4 NS 17875315
Resveratrol Drosophila melanogaster Canton S 1 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 10 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 32 µM -3.4 Female 17875315
Green tea polyphenols Mus musculus C57BL/6J (80 mg/l 6.4 0 17516143
Resveratrol Drosophila melanogaster Canton S 100 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 200 µM 0 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 1000 µM 3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 1 µM 0 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 3.2 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 3.2 µM 0 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 10 µM -7.7 Female 17875315
Resveratrol Drosophila melanogaster Canton S 32 µM -15.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 100 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 200 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 1000 µM -3.4 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 10 µM -8.3 Male 17875315
Resveratrol Drosophila melanogaster Canton S 1 µM 2.8 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 32 µM -13.9 Male 17875315
Resveratrol Drosophila melanogaster Canton S 3.2 µM -2.8 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 100 µM 2.8 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 1000 µM -8.3 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 1 µM -6.8 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 3.2 µM 4.5 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 200 µM 0 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 10 µM -4.5 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 32 µM 9.1 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 200 µM -4.5 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 1000 µM 4.5 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 100 µM 0 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 3.2 µM 8.2 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 10 µM 0 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 100 µM 0 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 32 µM -2 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 1000 µM -2 Male NS 17875315
Resveratrol Drosophila melanogaster Canton S 200 µM 2 Male NS 17875315
Resveratrol Drosophila melanogaster Dahomey 1 µM -5.6 Female NS 17875315
Resveratrol Drosophila melanogaster Canton S 1 µM 0 Male NS 17875315
Resveratrol Drosophila melanogaster Dahomey 3.2 µM -2.8 Female NS 17875315
Resveratrol Drosophila melanogaster Dahomey 10 µM -5.6 Female 17875315
Resveratrol Drosophila melanogaster Dahomey 32 µM -2.8 Female NS 17875315
Resveratrol Drosophila melanogaster Dahomey 200 µM -2.8 Female NS 17875315
Resveratrol Drosophila melanogaster Dahomey 1 µM 6.9 Female NS 17875315
Resveratrol Drosophila melanogaster Dahomey 100 µM 2.8 Female NS 17875315
Resveratrol Drosophila melanogaster Dahomey 1000 µM -5.6 Female NS 17875315

 (To Be Archived Only As Per Dr.Klatz)

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