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Gluten intolerance: Is the lack of Vitamin C and Probiotics to Blame?

By meisenstein at Sept. 26, 2013, 7:31 a.m., 31850 hits

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In a study published in the Journal of Allergologia et Immunopathologia researchers obtained biopsies from patients with celiac disease and added some ascorbate (vitamin C) to lab dishes containing gut tissue.
The effects were dramatic. The various inflammatory markers (INF-a & y, TNF, IL-13, 16, 17) were abolished in the vitamin C-treated dishes!

Will a shortage of Vitamin C reduce natural defenses against gluten? The evidence presented here points to another conclusion: Mankind is suffering from yet another manifestation of Vitamin C deficiency

European Journal of Clinical Nutrition
Published online ahead of print, doi: 10.1038/ejcn.2012.197

Led by Dr. Anurag Singh, the scientists recruited 20 people with seasonal allergic rhinitis to participate in their double-blinded, parallel, randomized placebo-controlled trial. Participants were randomly assigned to receive B. lactis NCC2818 (Probiotic) or placebo for eight weeks.
Results showed that markers of allergic responses in the blood were lower in the probiotic group compared with the placebo group. In addition, the researchers also looked at the activation levels of white blood cells that play a role in inflammatory reactions called basophils. Measuring the activation of basophils is a common tool to diagnose allergy. The new study revealed that activation of CD63 basophils was lower in the probiotic group after one month of supplementation…….

Dietary changes that include probiotics and/or prebiotics (found in some foods) and in supplements may help alleviate the severity of celiac/gluten sensitivity for some patients. According to a new research study appearing in the May 2010 print issue of the Journal of Leukocyte Biology, differing intestinal bacteria in celiac patients could influence inflammation to varying degrees. This suggests that manipulating the intestinal microbiota with dietary strategies such as probiotics and prebiotics, could improve the quality of life for celiac patients, as well as patients with associated diseases such as type 1 diabetes and other autoimmune disorders.

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— Last Edited by Mayer Eisenstein, MD, JD, MPH at 2013-09-28 10:08:04 —

Posts [ 1 ] | Last post Sept. 26, 2013, 7:31 a.m.
#1 - Sept. 26, 2013, 7:31 a.m.
Emma Brown

Doctors estimate that 1 percent of the population has celiac disease, which is damage to the small intestine caused by a severe allergic reaction to wheat gluten. Gluten is a protein found in wheat and wheat products. Even people who don't have celiac disease may display intestinal or immune system reactions to gluten, and doctors think that about 15 percent of the population may have a gluten sensitivity.While no medical test for gluten intolerance currently exists, you can take several steps to recognize gluten intolerance in your body and start down the road to a healthier future.

1. Pay attention to energy your energy level after you eat foods containing gluten. Occasionally, energy levels may slightly dip after consuming a large meal, while your body works to digest the food.

2. Examine your mental and emotional status after eating wheat or products containing wheat. Many individuals suffering from gluten intolerance complain of irritability after eating.

3. Notice when headaches develop after a meal. Headache symptoms are non-specific, and can mimic migraines, tension headaches or cluster headaches. While there is no specific type of headache associated with gluten intolerance, the headache pattern consistently occurs within 30 minutes to an hour after eating for many individuals.

4. Observe changes in your extremities. Often, people with gluten intolerance experience joint pain, and they sometimes experience numbness or tingling in their arms and legs.

5. Watch for symptoms associated with poor digestive health. While people with gluten sensitivity tend to have more non-gastrointestinal symptoms than people with celiac, they can still experience GI discomfort. After a meal, they may experience bloating, gas, diarrhea, constipation and stomach pain.