Changes in the brain caused by Alzheimer's disease are associated with shortening of the telomeres -- the protective caps on the ends of chromosomes that shorten as cells age -- according to a new study led by Anya Topiwala of Oxford Population Health, part of the University of Oxford, UK, published March 22 in the open-access journal PLOS ONE.
In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Universitu00e9 de Montru00e9al professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, is caused by irreversible damage to the genome rather than simply by telomere erosion.
Scientists from the University of Wisconsin Madison believe that they have solved an anti-aging mystery by identifying a gene that is responsible for cellular aging.
Research indicates that the average American lives to be around 75-80ish years old. The question is if you had the opportunity to live longer would you take it? This is a rather loaded question thick with philosophical and societal considerations among others.u00a0
Physical health is influenced by psychiatric disorders such as stress, anxiety and depression and they are all linked to increased risk of heart disease and shorter life expectancy; recent research suggests that this may be related to accelerated aging, finding that an effective form of psychological therapy can have protective physiological effects.u00a0
Mitochondria have been discovered to trigger senescence through communication with the cellu2019s nucleus, and an FDA approved drug has been revealed to help suppress the damaging effects of the condition in animal studies. Findings published in Genes & Development are hoped to eventually lead to treatments that may promote healthy aging and prevent age related diseases.
Highly active adults have telomeres with a biological aging advantage of nine years over those who are sedentary, and a seven-year advantage compared to those who are moderately active.
